Advancing RNAi Therapeutics

 
About Us
Sirnaomics, Inc. is a biopharmaceutical company discovering and developing novel targeted therapeutics for critical human diseases by using RNA interference (RNAi) technology. The company was founded in early 2007 with the mission of advancing RNAi technology using multi-targeted design of small interfering RNA (siRNA) and nanoparticle-enhanced delivery. The name of the company Sirnaomics (/ser-'now-miks/) is derived from the molecular terminology "siRNA" with the suffix "-omics" to signify the bridge between the study of the structure and function of small interfering RNAs (including their gene silencing properties) and the molecular comprehension of the complex interplay between genes these molecules target and pathways implicated in disease.   Read more...
 
News & Events
Dr. Patrick Lu Presents at AsiaTIDES Confe...
Sirnaomics Seals a Second Partnership Deal...
Sirnaomics Seals Partnership Deal for Deve...
Sirnaomics Selected to Present at October ...
Dr. Patrick Lu Appointed to Maryland's Nan...
Sirnaomics Receives Two SBIR Grants from N...
Sirnaomics Aims to Move Wound-Healing Drug...
Sirnaomics' Featured by GEN for Its Advanc...
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Products

 

Technologies
STP601 (Acurita) -
siRNA Therapeutics for AMD and Retinopathy
A multi-targeted siRNA cocktail nanoparticle formulation is developed for treatment of Age-related Macular Degeneration (AMD), Proliferative Diabetic Retinopathy (PDR) and Herpetic Stromal Keratitis (HSK), through intravitreous administration. This product has just completed a pre-IND meeting (May 14, 2008) with the USFDA and received a green light for IND enabling studies. Given a growing population of elderly and diabetics, blindness from these diseases is expected to be skyrocketing.        
STP705 (Cutasil®) -
siRNA Therapeutics for Skin Scarless Wound Healing
According to The Mattson Jack Group, an independent research group, the US commercial market for reduction of scarring in the skin is valued at approximately US$4 billion a year. There are some 42 million patients each year who could potentially benefit from pharmaceuticals that prevent or reduce scarring in the skin. There are 41.8 million surgical procedures to the skin each year in Europe and 70 million procedures annually in the United States involving wounds, which could benefit from a drug that improves the appearance of the scar. Currently there are no related pharmaceuticals available in the market either in the US or Europe.null
 

RNA Interference (RNAi) has emerged as a breakthrough in the life sciences industry. It presents extensive potential in multiple areas, such as drug discovery, drug development, and therapeutic applications for various indications along with aiding in the basic research. It has been found that, various components, such as siRNA & miRNA possess immense opportunities and provides a wide range in different drug classes. Besides, these molecules find wide applications in various sectors, such as functional genomics, disease diagnostics, and agriculture, among others. Many studies indicate that the usage of siRNA and miRNA in industries and academic institutions will witness ...  Read more

STP702 (FluQuit) -
siRNA Therapeutics against Influenza Infection
Our patented siRNA therapeutics shown to have efficacy against H5N1 (avian flu) have also demonstrated inhibitory activity against H1N1 (swine flu). With the recent pandemic of H1N1 the market for vaccines and therapeutics has increased dramatically in to $billions. With the rapid mutation rate of the flu virus we are seeing resistance to drugs such as amantadine and even tamiflu. Sirnaomics has licensed IP describing siRNA sequences for use in a therapeutic cocktail against flu and has identified a vehicle for administration of these siRNAs to the lung.

 
STP503 (Trisilensa) - 
siRNA Therapeutics for Breast Cancer 
More than 2 million women living in the U.S. have been treated for or are living with breast cancer, and more than 40,000 women are expected to die from the disease in 2006. Though breast cancer death rates are declining -- mostly due to earlier diagnosis -- the disease remains the second leading cause of cancer death in women (after lung cancer). Despite advances in detection, chemotherapy and other targeted therapeutic approaches, many women with breast cancer continue to die of this malignancy.
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